INterface BIOmaterials B.V. (founded in 2008) is an independent bioscience company with expertise in biomedical materials and medical devices. The company has a quality management system according to ISO 13485.
The company developed a proprietary new product for the embolization of uterine fibroids. The product, known as X-Spheres™, was CE certified in spring 2013.
The distinguishing unique feature of the X-Spheres™ is that the embolizing spherical microparticles are not only biocompatible but also radio-opaque. The spherical microparticles can be visualized through X-ray fluoroscopy, i.e. during the embolization procedure, and also afterwards. This feature will contribute to the efficacy and safety of embolization procedures.

- X-Spheres™ containing the dispersed embolizing microparticles
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- Demonstration of the X-ray visibility of the embolizing microparticles; the microparticles were injected into a rabbit kidney.
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